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IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

Rheumatoid arthritis (RA) and other autoimmune disorders are associated with altered activity of the immunomodulatory enzyme indoleamine-2,3-dioxygenase (IDO). However, the precise contributions of IDO function to autoimmunity remain unclear. Here, we examine the effect of two different IDO enzymes,...

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Detalhes bibliográficos
Main Authors: Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947779/
https://ncbi.nlm.nih.gov/pubmed/24489090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303012
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