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RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus
During the development of autoimmune disease, a switch occurs in the antibody repertoire of B cells so that the production of pathogenic rather than non-pathogenic autoantibodies is enabled. However, there is limited knowledge concerning how this pivotal step occurs. Here, we present genetic and pha...
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| 出版年: | Dis Model Mech |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719251/ https://ncbi.nlm.nih.gov/pubmed/28882929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029835 |
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