RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

During the development of autoimmune disease, a switch occurs in the antibody repertoire of B cells so that the production of pathogenic rather than non-pathogenic autoantibodies is enabled. However, there is limited knowledge concerning how this pivotal step occurs. Here, we present genetic and pha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dis Model Mech
Egile Nagusiak: Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719251/
https://ncbi.nlm.nih.gov/pubmed/28882929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029835
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