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The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity
Rheumatoid arthritis (RA) is a chronic and debilitating inflammatory autoimmune disease of unknown etiology. As with a variety of autoimmune disorders, evidence of elevated tryptophan catabolism has been detected in RA patients, indicative of activation of the immunomodulatory enzyme indoleamine 2,3...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741092/ https://ncbi.nlm.nih.gov/pubmed/19494274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804328 |
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