Antimetabolite TTL-315 selectively kills glucose-deprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer

Por DuHadaway, James, Prendergast, George C.
Publicado no Oncotarget (2016)

Specific in situ detection of murine indoleamine 2, 3-dioxygenase

Por Thomas, Sunil, DuHadaway, James, Prendergast, George C., Laury-Kleintop, Lisa
Publicado em 2014

RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

Por Huang, Minzhou, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado no Arterioscler Thromb Vasc Biol (2007)

Discovery of IDO1 inhibitors: from bench to bedside

Por Prendergast, George C., Malachowski, William P., DuHadaway, James B., Muller, Alexander J.
Publicado no Cancer Res (2017)

Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma

Por Ge, Kai, DuHadaway, James, Du, Wei, Herlyn, Meenhard, Rodeck, Ulrich, Prendergast, George C.
Publicado em 1999

RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC

Por Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado em 2011

Immunotherapeutic suppression of IDO and tumor growth with ethyl pyruvate

Por Muller, Alexander J., DuHadaway, James B., Jaller, Daniel, Curtis, Peter, Metz, Richard, Prendergast, George C.
Publicado em 2010

Regulation of Bcl-x(L) expression in human keratinocytes by cell–substratum adhesion and the epidermal growth factor receptor

Por Rodeck, Ulrich, Jost, Monika, DuHadaway, James, Kari, Csaba, Jensen, Pamela J., Risse, Barbara, Ewert, Donald L.
Publicado em 1997

CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL

Por Eldredge, Harriet Belding, DeNittis, Albert, DuHadaway, James B., Chernick, Michael, Metz, Richard, Prendergast, George C.
Publicado em 2013

1-Methyl-Tryptophan Synergizes with Methotrexate to Alleviate Arthritis in a Mouse Model of Arthritis

Por Pigott, Elizabeth, DuHadaway, James B., Muller, Alexander J., Gilmour, Susan, Prendergast, George C., Mandik-Nayak, Laura
Publicado no Autoimmunity (2014)

The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity

Por Scott, Grant N., DuHadaway, James, Pigott, Elizabeth, Ridge, Natalie, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Publicado em 2009

Zinc protoporphyrin-IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase

Por Metz, Richard, DuHadaway, James B., Rust, Sonja, Munn, David H., Muller, Alexander J., Mautino, Mario, Prendergast, George C.
Publicado em 2010

IDO2 modulates T cell-dependent autoimmune responses through a B cell-intrinsic mechanism

Por Merlo, Lauren M.F., DuHadaway, James B., Grabler, Samantha, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Publicado no J Immunol (2016)

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

Por Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Publicado em 2014

IDO1 is an Integral Mediator of Inflammatory Neovascularization

Por Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Publicado no EBioMedicine (2016)

Structure-Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors

Por Gaspari, Paul, Banerjee, Tinku, Malachowski, William P., Muller, Alexander J., Prendergast, George C., DuHadaway, James, Bennett, Shauna, Donovan, Ashley M.
Publicado em 2006

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

Por Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado no Dis Model Mech (2017)

Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

Por Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Publicado em 2008

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Por Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Publicado em 2012

Therapeutic Antibody Targeting of Indoleamine-2,3-Dioxygenase (IDO2) Inhibits Autoimmune Arthritis

Por Merlo, Lauren M.F., Grabler, Samantha, DuHadaway, James B., Pigott, Elizabeth, Manley, Kaylend, Prendergast, George C., Laury-Kleintop, Lisa D., Mandik-Nayak, Laura
Publicado no Clin Immunol (2017)