Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

Indoleamine 2,3-dioxygenase (IDO) modifies adaptive immunity, in part by determining the character of inflammatory responses in the tissue microenvironment. Small molecule inhibitors of IDO are being developed to treat cancer, chronic infections and other diseases, so the systemic effects of IDO dis...

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Detalhes bibliográficos
Main Authors: Chang, Mee Young, Smith, Courtney, DuHadaway, James B, Pyle, Jennifer R, Boulden, Janette, Soler, Alejandro Peralta, Muller, Alexander J, Laury-Kleintop, Lisa D, Prendergast, George C
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335939/
https://ncbi.nlm.nih.gov/pubmed/22157149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.12.18142
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