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Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
Genetic and pharmacological studies of indoleamine 2,3-dioxygenase (IDO) have established this tryptophan catabolic enzyme as a central driver of malignant development and progression. IDO acts in tumor, stromal and immune cells to support pathogenic inflammatory processes that engender immune toler...
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| Published in: | Cancer Immunol Immunother |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Berlin Heidelberg
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384696/ https://ncbi.nlm.nih.gov/pubmed/24711084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-014-1549-4 |
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