Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors

Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. While small molecule inhibitors of IDO exist, there remains a dearth of high-potency compou...

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Bibliografiska uppgifter
I publikationen:J Med Chem
Huvudupphovsmän: Kumar, Sanjeev, Malachowski, William P., DuHadaway, James B., LaLonde, Judith M., Carroll, Patrick J., Jaller, Daniel, Metz, Richard, Prendergast, George C., Muller, Alexander J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384695/
https://ncbi.nlm.nih.gov/pubmed/18318466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm7014155
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