Antimetabolite TTL-315 selectively kills glucose-deprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer

door DuHadaway, James, Prendergast, George C.
Gepubliceerd in Oncotarget (2016)

Specific in situ detection of murine indoleamine 2, 3-dioxygenase

door Thomas, Sunil, DuHadaway, James, Prendergast, George C., Laury-Kleintop, Lisa
Gepubliceerd in 2014

RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

door Huang, Minzhou, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Gepubliceerd in Arterioscler Thromb Vasc Biol (2007)

Discovery of IDO1 inhibitors: from bench to bedside

door Prendergast, George C., Malachowski, William P., DuHadaway, James B., Muller, Alexander J.
Gepubliceerd in Cancer Res (2017)

Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma

door Ge, Kai, DuHadaway, James, Du, Wei, Herlyn, Meenhard, Rodeck, Ulrich, Prendergast, George C.
Gepubliceerd in 1999

RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC

door Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Gepubliceerd in 2011

Immunotherapeutic suppression of IDO and tumor growth with ethyl pyruvate

door Muller, Alexander J., DuHadaway, James B., Jaller, Daniel, Curtis, Peter, Metz, Richard, Prendergast, George C.
Gepubliceerd in 2010

Regulation of Bcl-x(L) expression in human keratinocytes by cell–substratum adhesion and the epidermal growth factor receptor

door Rodeck, Ulrich, Jost, Monika, DuHadaway, James, Kari, Csaba, Jensen, Pamela J., Risse, Barbara, Ewert, Donald L.
Gepubliceerd in 1997

CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL

door Eldredge, Harriet Belding, DeNittis, Albert, DuHadaway, James B., Chernick, Michael, Metz, Richard, Prendergast, George C.
Gepubliceerd in 2013

1-Methyl-Tryptophan Synergizes with Methotrexate to Alleviate Arthritis in a Mouse Model of Arthritis

door Pigott, Elizabeth, DuHadaway, James B., Muller, Alexander J., Gilmour, Susan, Prendergast, George C., Mandik-Nayak, Laura
Gepubliceerd in Autoimmunity (2014)

The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity

door Scott, Grant N., DuHadaway, James, Pigott, Elizabeth, Ridge, Natalie, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Gepubliceerd in 2009

Zinc protoporphyrin-IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase

door Metz, Richard, DuHadaway, James B., Rust, Sonja, Munn, David H., Muller, Alexander J., Mautino, Mario, Prendergast, George C.
Gepubliceerd in 2010

IDO2 modulates T cell-dependent autoimmune responses through a B cell-intrinsic mechanism

door Merlo, Lauren M.F., DuHadaway, James B., Grabler, Samantha, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Gepubliceerd in J Immunol (2016)

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

door Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Gepubliceerd in 2014

IDO1 is an Integral Mediator of Inflammatory Neovascularization

door Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Gepubliceerd in EBioMedicine (2016)

Structure-Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors

door Gaspari, Paul, Banerjee, Tinku, Malachowski, William P., Muller, Alexander J., Prendergast, George C., DuHadaway, James, Bennett, Shauna, Donovan, Ashley M.
Gepubliceerd in 2006

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

door Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Gepubliceerd in Dis Model Mech (2017)

Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

door Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Gepubliceerd in 2008

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

door Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Gepubliceerd in 2012

Therapeutic Antibody Targeting of Indoleamine-2,3-Dioxygenase (IDO2) Inhibits Autoimmune Arthritis

door Merlo, Lauren M.F., Grabler, Samantha, DuHadaway, James B., Pigott, Elizabeth, Manley, Kaylend, Prendergast, George C., Laury-Kleintop, Lisa D., Mandik-Nayak, Laura
Gepubliceerd in Clin Immunol (2017)