Antimetabolite TTL-315 selectively kills glucose-deprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer

von DuHadaway, James, Prendergast, George C.
Veröffentlicht in Oncotarget (2016)

Specific in situ detection of murine indoleamine 2, 3-dioxygenase

von Thomas, Sunil, DuHadaway, James, Prendergast, George C., Laury-Kleintop, Lisa
Veröffentlicht 2014

RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells

von Huang, Minzhou, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Veröffentlicht in Arterioscler Thromb Vasc Biol (2007)

Discovery of IDO1 inhibitors: from bench to bedside

von Prendergast, George C., Malachowski, William P., DuHadaway, James B., Muller, Alexander J.
Veröffentlicht in Cancer Res (2017)

Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma

von Ge, Kai, DuHadaway, James, Du, Wei, Herlyn, Meenhard, Rodeck, Ulrich, Prendergast, George C.
Veröffentlicht 1999

RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC

von Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.
Veröffentlicht 2011

Immunotherapeutic suppression of IDO and tumor growth with ethyl pyruvate

von Muller, Alexander J., DuHadaway, James B., Jaller, Daniel, Curtis, Peter, Metz, Richard, Prendergast, George C.
Veröffentlicht 2010

Regulation of Bcl-x(L) expression in human keratinocytes by cell–substratum adhesion and the epidermal growth factor receptor

von Rodeck, Ulrich, Jost, Monika, DuHadaway, James, Kari, Csaba, Jensen, Pamela J., Risse, Barbara, Ewert, Donald L.
Veröffentlicht 1997

CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL

von Eldredge, Harriet Belding, DeNittis, Albert, DuHadaway, James B., Chernick, Michael, Metz, Richard, Prendergast, George C.
Veröffentlicht 2013

1-Methyl-Tryptophan Synergizes with Methotrexate to Alleviate Arthritis in a Mouse Model of Arthritis

von Pigott, Elizabeth, DuHadaway, James B., Muller, Alexander J., Gilmour, Susan, Prendergast, George C., Mandik-Nayak, Laura
Veröffentlicht in Autoimmunity (2014)

The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity

von Scott, Grant N., DuHadaway, James, Pigott, Elizabeth, Ridge, Natalie, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Veröffentlicht 2009

Zinc protoporphyrin-IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase

von Metz, Richard, DuHadaway, James B., Rust, Sonja, Munn, David H., Muller, Alexander J., Mautino, Mario, Prendergast, George C.
Veröffentlicht 2010

IDO2 modulates T cell-dependent autoimmune responses through a B cell-intrinsic mechanism

von Merlo, Lauren M.F., DuHadaway, James B., Grabler, Samantha, Prendergast, George C., Muller, Alexander J., Mandik-Nayak, Laura
Veröffentlicht in J Immunol (2016)

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis()

von Merlo, Lauren M.F., Pigott, Elizabeth, DuHadaway, James B., Grabler, Samantha, Metz, Richard, Prendergast, George C., Mandik-Nayak, Laura
Veröffentlicht 2014

IDO1 is an Integral Mediator of Inflammatory Neovascularization

von Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Veröffentlicht in EBioMedicine (2016)

Structure-Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors

von Gaspari, Paul, Banerjee, Tinku, Malachowski, William P., Muller, Alexander J., Prendergast, George C., DuHadaway, James, Bennett, Shauna, Donovan, Ashley M.
Veröffentlicht 2006

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

von Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Veröffentlicht in Dis Model Mech (2017)

Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

von Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Veröffentlicht 2008

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

von Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Veröffentlicht 2012

Therapeutic Antibody Targeting of Indoleamine-2,3-Dioxygenase (IDO2) Inhibits Autoimmune Arthritis

von Merlo, Lauren M.F., Grabler, Samantha, DuHadaway, James B., Pigott, Elizabeth, Manley, Kaylend, Prendergast, George C., Laury-Kleintop, Lisa D., Mandik-Nayak, Laura
Veröffentlicht in Clin Immunol (2017)