Sequence-specific backbone (1)H, (13)C, and (15)N resonance assignments of human ribonuclease 4

Por Gagné, Donald, Doucet, Nicolas
Publicado no Biomol NMR Assign (2014)

Systematic Mutational Analysis of the Putative Hydrolase PqsE: Toward a Deeper Molecular Understanding of Virulence Acquisition in Pseudomonas aeruginosa

Por Folch, Benjamin, Déziel, Eric, Doucet, Nicolas
Publicado em 2013

Correction: Systematic Mutational Analysis of the Putative Hydrolase PqsE: Toward a Deeper Molecular Understanding of Virulence Acquisition in Pseudomonas aeruginosa

Por Folch, Benjamin, Déziel, Eric, Doucet, Nicolas
Publicado em 2014

Network of long-range concerted chemical shift displacements upon ligand binding to human angiogenin

Por Gagné, Donald, Narayanan, Chitra, Doucet, Nicolas
Publicado no Protein Sci (2015)

Role of Conformational Motions in Enzyme Function: Selected Methodologies and Case Studies

Por Narayanan, Chitra, Bernard, David N., Doucet, Nicolas
Publicado no Catalysts (2016)

The Flexibility of a Distant Loop Modulates Active-Site Motion and Product Release in Ribonuclease A

Por Doucet, Nicolas, Watt, Eric D., Loria, J. Patrick
Publicado em 2009

High tolerance to simultaneous active-site mutations in TEM-1 β-lactamase: Distinct mutational paths provide more generalized β-lactam recognition

Por De Wals, Pierre-Yves, Doucet, Nicolas, Pelletier, Joelle N
Publicado em 2009

Combinatorial active-site variants confer sustained clavulanate resistance in BlaC β-lactamase from Mycobacterium tuberculosis

Por Egesborg, Philippe, Carlettini, Hélène, Volpato, Jordan P, Doucet, Nicolas
Publicado no Protein Sci (2015)

Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

Por Narayanan, Chitra, Gagné, Donald, Reynolds, Kimberly A., Doucet, Nicolas
Publicado no Sci Rep (2017)

Isolation and Characterization of EstC, a New Cold-Active Esterase from Streptomyces coelicolor A3(2)

Por Brault, Guillaume, Shareck, François, Hurtubise, Yves, Lépine, François, Doucet, Nicolas
Publicado em 2012

Short-Chain Flavor Ester Synthesis in Organic Media by an E. coli Whole-Cell Biocatalyst Expressing a Newly Characterized Heterologous Lipase

Por Brault, Guillaume, Shareck, François, Hurtubise, Yves, Lépine, François, Doucet, Nicolas
Publicado em 2014

Conformational Sub-states and Populations in Enzyme Catalysis

Por Agarwal, Pratul K., Doucet, Nicolas, Chennubhotla, Chakra, Ramanathan, Arvind, Narayanan, Chitra
Publicado no Methods Enzymol (2016)

(15)N, (13)C and (1)H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant

Por Gobeil, Sophie M. C., Gagné, Donald, Doucet, Nicolas, Pelletier, Joelle N.
Publicado no Biomol NMR Assign (2015)

Conservation of Flexible Residue Clusters among Structural and Functional Enzyme Homologues

Por Gagné, Donald, Charest, Laurie-Anne, Morin, Sébastien, Kovrigin, Evgenii L., Doucet, Nicolas
Publicado em 2012

Applications of NMR and computational methodologies to study protein dynamics

Por Narayanan, Chitra, Bafna, Khushboo, Roux, Louise D., Agarwal, Pratul K., Doucet, Nicolas
Publicado no Arch Biochem Biophys (2017)

Perturbation of the conformational dynamics of an active-site loop alters enzyme activity

Por Gagné, Donald, French, Rachel L., Narayanan, Chitra, Simonović, Miljan, Agarwal, Pratul K., Doucet, Nicolas
Publicado no Structure (2015)

Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin

Por Gagné, Donald, Narayanan, Chitra, Bafna, Khushboo, Charest, Laurie-Anne, Agarwal, Pratul K., Doucet, Nicolas
Publicado no Biomol NMR Assign (2017)

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

Por Narayanan, Chitra, Bernard, David N., Bafna, Khushboo, Gagné, Donald, Agarwal, Pratul K., Doucet, Nicolas
Publicado no Front Mol Biosci (2018)

Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily

Por Narayanan, Chitra, Bernard, David N., Bafna, Khushboo, Gagné, Donald, Chennubhotla, Chakra S., Doucet, Nicolas, Agarwal, Pratul K.
Publicado no Structure (2018)

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells

Por Grosset, Andrée-Anne, Labrie, Marilyne, Gagné, Donald, Vladoiu, Maria-Claudia, Gaboury, Louis, Doucet, Nicolas, St-Pierre, Yves
Publicado no BMC Cancer (2014)