Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells

BACKGROUND: Resistance to apoptosis induced by anti-cancer drugs is a major obstacle for the treatment of aggressive forms of breast cancer. Galectin-7 (gal-7) was recently shown to be specifically expressed in basal-like but not in luminal subtypes of human breast cancer. METHODS: We generated a mu...

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Udgivet i:BMC Cancer
Main Authors: Grosset, Andrée-Anne, Labrie, Marilyne, Gagné, Donald, Vladoiu, Maria-Claudia, Gaboury, Louis, Doucet, Nicolas, St-Pierre, Yves
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228062/
https://ncbi.nlm.nih.gov/pubmed/25367122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-801
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