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(15)N, (13)C and (1)H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant

The widespread use of β-lactam antibiotics has given rise to a dramatic increase in clinically-relevant β-lactamases. Understanding the structure/function relation in these variants is essential to better address the ever-growing incidence of antibiotic resistance. We previously reported the backbon...

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Detalhes bibliográficos
Publicado no:Biomol NMR Assign
Main Authors: Gobeil, Sophie M. C., Gagné, Donald, Doucet, Nicolas, Pelletier, Joelle N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419827/
https://ncbi.nlm.nih.gov/pubmed/26386961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-015-9645-8
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