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Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily
In this work, we applied the sequence-based statistical coupling analysis approach to characterize conserved amino acid networks important for biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily. This superfamily-wide analysis indicates a decomposition of the RNase tertiar...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466627/ https://ncbi.nlm.nih.gov/pubmed/28600532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03298-4 |
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