APPL1: role in adiponectin signaling and beyond

Por Deepa, Sathyaseelan S., Dong, Lily Q.
Publicado em 2009

Adiponectin signaling and function in insulin target tissues

Por Ruan, Hong, Dong, Lily Q.
Publicado no J Mol Cell Biol (2016)

Ursolic Acid Inhibits Leucine-Stimulated mTORC1 Signaling by Suppressing mTOR Localization to Lysosome

Por Ou, Xiang, Liu, Meilian, Luo, Hairong, Dong, Lily Q., Liu, Feng
Publicado em 2014

Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function

Por Lim, Mei A., Kikani, Chintan K., Wick, Michael J., Dong, Lily Q.
Publicado em 2003

APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway

Por Xin, Xiaoban, Zhou, Lijun, Reyes, Caleb M., Liu, Feng, Dong, Lily Q.
Publicado em 2011

DsbA-L Alleviates Endoplasmic Reticulum Stress–Induced Adiponectin Downregulation

Por Zhou, Lijun, Liu, Meilian, Zhang, Jingjing, Chen, Hongzhi, Dong, Lily Q., Liu, Feng
Publicado em 2010

Adiponectin Inhibits Osteoclastogenesis and Bone Resorption via APPL1-mediated Suppression of Akt1

Por Tu, Qisheng, Zhang, Jin, Dong, Lily Q., Saunders, Eileen, Luo, En, Tang, Jean, Chen, Jake
Publicado em 2011

Appl1 and Appl2 are Expendable for Mouse Development but are Essential for HGF-induced Akt Activation and Migration in Mouse Embryonic Fibroblasts

Por Tan, Yinfei, Xin, Xiaoban, Coffey, Francis J., Wiest, David L., Dong, Lily Q., Testa, Joseph R.
Publicado no J Cell Physiol (2015)

Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton

Por Dong, Lily Q., Landa, Luis R., Wick, Michael J., Zhu, Li, Mukai, Hideyuki, Ono, Yoshitaka, Liu, Feng
Publicado em 2000

Autophagy-Mediated Insulin Receptor Down-Regulation Contributes to Endoplasmic Reticulum Stress-Induced Insulin Resistance

Por Zhou, Lijun, Zhang, Jingjing, Fang, Qichen, Liu, Meilian, Liu, Xianling, Jia, Weiping, Dong, Lily Q., Liu, Feng
Publicado em 2009

Endoplasmic Reticulum (ER) Localization Is Critical for DsbA-L Protein to Suppress ER Stress and Adiponectin Down-regulation in Adipocytes

Por Liu, Meilian, Chen, Hongzhi, Wei, Li, Hu, Derong, Dong, Kun, Jia, Weiping, Dong, Lily Q., Liu, Feng
Publicado no J Biol Chem (2015)

Up-regulation of Adiponectin by Resveratrol: THE ESSENTIAL ROLES OF THE Akt/FOXO1 AND AMP-ACTIVATED PROTEIN KINASE SIGNALING PATHWAYS AND DsbA-L

Por Wang, Anping, Liu, Meilian, Liu, Xianling, Dong, Lily Q., Glickman, Randolph D., Slaga, Thomas J., Zhou, Zhiguang, Liu, Feng
Publicado em 2011

Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR

Por Liu, Meilian, Wilk, Sarah Ann, Wang, Anping, Zhou, Lijun, Wang, Rui-Hong, Ogawa, Wataru, Deng, Chuxia, Dong, Lily Q., Liu, Feng
Publicado em 2010

A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization

Por Liu, Meilian, Zhou, Lijun, Xu, Aimin, Lam, Karen S. L., Wetzel, Michael D., Xiang, Ruihua, Zhang, Jingjing, Xin, Xiaoban, Dong, Lily Q., Liu, Feng
Publicado em 2008

Downregulation of Grb2 contributes to the insulin-sensitizing effect of calorie restriction

Por Liu, Xianling, Liu, Meilian, Zhang, Jingjing, Bai, Xiang, Ramos, Fresnida, Van Remmen, Holly, Richardson, Arlan, Liu, Fu-You, Dong, Lily Q., Liu, Feng
Publicado em 2009

The Trifunctional Protein Mediates Thyroid Hormone Receptor-Dependent Stimulation of Mitochondria Metabolism

Por Chocron, E. Sandra, Sayre, Naomi L., Holstein, Deborah, Saelim, Nuttawut, Ibdah, Jamal A., Dong, Lily Q., Zhu, Xuguang, Cheng, Sheue-Yann, Lechleiter, James D.
Publicado em 2012

APPL1 Mediates Adiponectin-Induced LKB1 Cytosolic Localization Through the PP2A-PKCζ Signaling Pathway

Por Deepa, Sathyaseelan S., Zhou, Lijun, Ryu, Jiyoon, Wang, Changhua, Mao, Xuming, Li, Cai, Zhang, Ning, Musi, Nicolas, DeFronzo, Ralph A., Liu, Feng, Dong, Lily Q.
Publicado em 2011

Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice

Por Wu, Yuwei, Tu, Qisheng, Valverde, Paloma, Zhang, Jin, Murray, Dana, Dong, Lily Q., Cheng, Jessica, Jiang, Hua, Rios, Maribel, Morgan, Elise, Tang, Zhihui, Chen, Jake
Publicado em 2014

Yin-Yang Regulation of Adiponectin Signaling by APPL Isoforms in Muscle Cells

Por Wang, Changhua, Xin, Xiaoban, Xiang, Ruihua, Ramos, Fresnida J., Liu, Meilian, Lee, Hak Joo, Chen, Hongzhi, Mao, Xuming, Kikani, Chintan K., Liu, Feng, Dong, Lily Q.
Publicado em 2009

Phosphorylation of Adaptor Protein Containing Pleckstrin Homology Domain, Phosphotyrosine Binding Domain, and Leucine Zipper Motif 1 (APPL1) at Ser(430) Mediates Endoplasmic Reticu...

Por Liu, Meilian, Zhou, Lijun, Wei, Li, Villarreal, Ricardo, Yang, Xin, Hu, Derong, Riojas, Ramon A., Holmes, Bekke M., Langlais, Paul R., Lee, Hakjoo, Dong, Lily Q.
Publicado em 2012