Autophagy-Mediated Insulin Receptor Down-Regulation Contributes to Endoplasmic Reticulum Stress-Induced Insulin Resistance

Endoplasmic reticulum (ER) stress is associated with obesity-induced insulin resistance, yet the underlying mechanisms remain to be fully elucidated. Here we show that ER stress-induced insulin receptor (IR) down-regulation may play a critical role in obesity-induced insulin resistance. The expressi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhou, Lijun, Zhang, Jingjing, Fang, Qichen, Liu, Meilian, Liu, Xianling, Jia, Weiping, Dong, Lily Q., Liu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730390/
https://ncbi.nlm.nih.gov/pubmed/19541767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.057067
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados