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Appl1 and Appl2 are Expendable for Mouse Development but are Essential for HGF-induced Akt Activation and Migration in Mouse Embryonic Fibroblasts

Although Appl1 and Appl2 have been implicated in multiple cellular activities, we and others have found that Appl1 is dispensable for mouse embryonic development, suggesting that Appl2 can substitute for Appl1 during development. To address this possibility, we generated conditionally targeted Appl2...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Tan, Yinfei, Xin, Xiaoban, Coffey, Francis J., Wiest, David L., Dong, Lily Q., Testa, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728037/
https://ncbi.nlm.nih.gov/pubmed/26445298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25211
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