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Ursolic Acid Inhibits Leucine-Stimulated mTORC1 Signaling by Suppressing mTOR Localization to Lysosome

Ursolic acid (UA), a pentacyclic triterpenoid widely found in medicinal herbs and fruits, has been reported to possess a wide range of beneficial properties including anti-hyperglycemia, anti-obesity, and anti-cancer. However, the molecular mechanisms underlying the action of UA remain largely unkno...

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Detalhes bibliográficos
Main Authors: Ou, Xiang, Liu, Meilian, Luo, Hairong, Dong, Lily Q., Liu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989317/
https://ncbi.nlm.nih.gov/pubmed/24740400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095393
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