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FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1
The intracellular amino acid pool within lysosome is a signal that stimulates the nutrient-sensing mTORC1 signalling pathway. The signal transduction cascade has garnered much attention, but little is known about the sequestration of the signalling molecules within the lysosome. Using human HEK293 c...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900541/ https://ncbi.nlm.nih.gov/pubmed/27280402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157100 |
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