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FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1
The intracellular amino acid pool within lysosome is a signal that stimulates the nutrient-sensing mTORC1 signalling pathway. The signal transduction cascade has garnered much attention, but little is known about the sequestration of the signalling molecules within the lysosome. Using human HEK293 c...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900541/ https://ncbi.nlm.nih.gov/pubmed/27280402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157100 |
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