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Suppressing mTORC1 on the lysosome
The mechanistic target of rapamycin, mTOR, is a protein kinase that integrates environmental and nutritional inputs into regulation of cell growth and metabolism. Key outputs of mTOR signalling occur from the lysosome membrane in the form of the multi‐subunit mTOR complex 1 (mTORC1), which phosphory...
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| Udgivet i: | EMBO J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502876/ https://ncbi.nlm.nih.gov/pubmed/28623241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797469 |
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