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Suppressing mTORC1 on the lysosome

The mechanistic target of rapamycin, mTOR, is a protein kinase that integrates environmental and nutritional inputs into regulation of cell growth and metabolism. Key outputs of mTOR signalling occur from the lysosome membrane in the form of the multi‐subunit mTOR complex 1 (mTORC1), which phosphory...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Raiborg, Camilla, Schink, Kay O, Stenmark, Harald
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502876/
https://ncbi.nlm.nih.gov/pubmed/28623241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797469
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