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Suppressing mTORC1 on the lysosome

The mechanistic target of rapamycin, mTOR, is a protein kinase that integrates environmental and nutritional inputs into regulation of cell growth and metabolism. Key outputs of mTOR signalling occur from the lysosome membrane in the form of the multi‐subunit mTOR complex 1 (mTORC1), which phosphory...

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Bibliographic Details
Published in:EMBO J
Main Authors: Raiborg, Camilla, Schink, Kay O, Stenmark, Harald
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502876/
https://ncbi.nlm.nih.gov/pubmed/28623241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797469
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