In vitro evolution of distinct self-cleaving ribozymes in diverse environments

Por Popović, Milena, Fliss, Palmer S., Ditzler, Mark A.
Publicado no Nucleic Acids Res (2015)

Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme

Por Ditzler, Mark A., Šponer, Jiří, Walter, Nils G.
Publicado em 2009

Molecular Dynamics and Quantum Mechanics of RNA: Conformational and Chemical Change We Can Believe In

Por Ditzler, Mark A., Otyepka, Michal, Šponer, Jiřì, Walter, Nils G.
Publicado em 2009

Evolution of ribozymes in the presence of a mineral surface

Por Stephenson, James D., Popović, Milena, Bristow, Thomas F., Ditzler, Mark A.
Publicado no RNA (2016)

A rugged free energy landscape separates multiple functional RNA folds throughout denaturation

Por Ditzler, Mark A., Rueda, David, Mo, Jingjie, Håkansson, Kristina, Walter, Nils G.
Publicado em 2008

Big on Change, Small on Innovation: Evolutionary Consequences of RNA Sequence Duplication

Por Plebanek, Andrew, Larnerd, Caleb, Popović, Milena, Wei, Chenyu, Pohorille, Andrew, Ditzler, Mark A.
Publicado no J Mol Evol (2019)

In vitro selections with RNAs of variable length converge on a robust catalytic core

Por Popović, Milena, Ellingson, Alexander Q, Chu, Theresa P, Wei, Chenyu, Pohorille, Andrew, Ditzler, Mark A
Publicado no Nucleic Acids Res (2020)

Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates

Por Ditzler, Mark A., Bose, Debojit, Shkriabai, Nikolozi, Marchand, Bruno, Sarafianos, Stefan G., Kvaratskhelia, Mamuka, Burke, Donald H.
Publicado em 2011

Selection of 2′-Deoxy-2′-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV-1 Integrase with Picomolar Affinity

Por Rose, Kevin M., Alves Ferreira-Bravo, Irani, Li, Min, Craigie, Robert, Ditzler, Mark A., Holliger, Philipp, DeStefano, Jeffrey J.
Publicado no ACS Chem Biol (2019)

Potent Inhibition of HIV-1 Reverse Transcriptase and Replication by Nonpseudoknot, “UCAA-motif” RNA Aptamers

Por Whatley, Angela S, Ditzler, Mark A, Lange, Margaret J, Biondi, Elisa, Sawyer, Andrew W, Chang, Jonathan L, Franken, Joshua D, Burke, Donald H
Publicado em 2013

High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase

Por Ditzler, Mark A., Lange, Margaret J., Bose, Debojit, Bottoms, Christopher A., Virkler, Katherine F., Sawyer, Andrew W., Whatley, Angela S., Spollen, William, Givan, Scott A., Burke, Donald H.
Publicado em 2013

Conformational dynamics of single pre–mRNA molecules during in vitro splicing

Por Abelson, John, Blanco, Mario, Ditzler, Mark A., Fuller, Franklin, Aravamudhan, Pavithra, Wood, Mona, Villa, Tommaso, Ryan, Daniel E., Pleiss, Jeffrey A., Maeder, Corina, Guthrie, Christine, Walter, Nils G.
Publicado em 2010