SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status

Por Yu, Wei, Dittenhafer-Reed, Kristin E., Denu, John M.
Publicado em 2012

Catalysis and mechanistic insights on Sirtuin activation

Por Dittenhafer-Reed, Kristin E., Feldman, Jessica L., Denu, John M.
Publicado em 2010

Sirtuin Catalysis and Regulation

Por Feldman, Jessica L., Dittenhafer-Reed, Kristin E., Denu, John M.
Publicado em 2012

Kinetic and structural basis for acyl-group selectivity and NAD(+)-dependence in Sirtuin-catalyzed deacylation

Por Feldman, Jessica L., Dittenhafer-Reed, Kristin E., Kudo, Norio, Thelen, Julie N., Ito, Akihiro, Yoshida, Minoru, Denu, John M.
Publicado no Biochemistry (2015)

SIRT3 mediates multi-tissue coupling for metabolic fuel switching

Por Dittenhafer-Reed, Kristin E., Richards, Alicia L., Fan, Jing, Smallegan, Michael J., Siahpirani, Alireza Fotuhi, Kemmerer, Zachary A., Prolla, Tomas A., Roy, Sushmita, Coon, Joshua J., Denu, John M.
Publicado no Cell Metab (2015)

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

Por Shimazu, Tadahiro, Hirschey, Matthew D., Hua, Lan, Dittenhafer-Reed, Kristin E., Schwer, Bjoern, Lombard, David B., Li, Yu, Bunkenborg, Jakob, Alt, Frederick W., Denu, John M., Jacobson, Matthew P., Verdin, Eric
Publicado em 2010

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

Por Hebert, Alexander S., Dittenhafer-Reed, Kristin E., Yu, Wei, Bailey, Derek J., Selen, Ebru Selin, Boersma, Melissa D., Carson, Joshua J., Tonelli, Marco, Balloon, Allison, Higbee, Alan J., Westphall, Michael S., Pagliarini, David J., Prolla, Tomas A., Assadi-Porter, Fariba, Roy, Sushmita, Denu, John M., Coon, Joshua J.
Publicado em 2012

Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation

Por Still, Amelia J., Floyd, Brendan J., Hebert, Alexander S., Bingman, Craig A., Carson, Joshua J., Gunderson, Drew R., Dolan, Brendan K., Grimsrud, Paul A., Dittenhafer-Reed, Kristin E., Stapleton, Donald S., Keller, Mark P., Westphall, Michael S., Denu, John M., Attie, Alan D., Coon, Joshua J., Pagliarini, David J.
Publicado em 2013

The genomic landscape of tuberous sclerosis complex

Por Martin, Katie R., Zhou, Wanding, Bowman, Megan J., Shih, Juliann, Au, Kit Sing, Dittenhafer-Reed, Kristin E., Sisson, Kellie A., Koeman, Julie, Weisenberger, Daniel J., Cottingham, Sandra L., DeRoos, Steven T., Devinsky, Orrin, Winn, Mary E., Cherniack, Andrew D., Shen, Hui, Northrup, Hope, Krueger, Darcy A., MacKeigan, Jeffrey P.
Publicado no Nat Commun (2017)