SIRT3 mediates multi-tissue coupling for metabolic fuel switching

SIRT3 is a member of the Sirtuin family of NAD(+)-dependent deacylases and plays a critical role in metabolic regulation. Organism-wide SIRT3 loss manifests in metabolic alterations, however the coordinating role of SIRT3 among metabolically distinct tissues is unknown. Using multi-tissue quantitati...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Dittenhafer-Reed, Kristin E., Richards, Alicia L., Fan, Jing, Smallegan, Michael J., Siahpirani, Alireza Fotuhi, Kemmerer, Zachary A., Prolla, Tomas A., Roy, Sushmita, Coon, Joshua J., Denu, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393847/
https://ncbi.nlm.nih.gov/pubmed/25863253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.03.007
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