The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock Response

Por Dinkova-Kostova, Albena T.
Publicado em 2012

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

Por Dinkova-Kostova, Albena T., Talalay, Paul
Publicado em 2010

The emerging role of Nrf2 in mitochondrial function

Por Dinkova-Kostova, Albena T., Abramov, Andrey Y.
Publicado no Free Radic Biol Med (2015)

Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of...

Por Gao, Xiangqun, Dinkova-Kostova, Albena T., Talalay, Paul
Publicado em 2001

Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles

Por Liu, Hua, Dinkova-Kostova, Albena T., Talalay, Paul
Publicado em 2008

Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants()

Por Dinkova-Kostova, Albena T., Kostov, Rumen V., Canning, Peter
Publicado no Arch Biochem Biophys (2017)

The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress

Por Benedict, Andrea L., Knatko, Elena V., Dinkova-Kostova, Albena T.
Publicado em 2012

Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

Por Baird, Liam, Llères, David, Swift, Sam, Dinkova-Kostova, Albena T.
Publicado em 2013

Monitoring Keap1–Nrf2 interactions in single live cells

Por Baird, Liam, Swift, Sam, Llères, David, Dinkova-Kostova, Albena T.
Publicado em 2014

The multifaceted role of Nrf2 in mitochondrial function

Por Holmström, Kira M., Kostov, Rumen V., Dinkova-Kostova, Albena T.
Publicado no Curr Opin Toxicol (2016)

Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma

Por Knatko, Elena V., Higgins, Maureen, Fahey, Jed W., Dinkova-Kostova, Albena T.
Publicado no Sci Rep (2016)

Efficacy ranking of triterpenoids as inducers of a cytoprotective enzyme and as inhibitors of a cellular inflammatory response via their electron affinity and their electrophilicit...

Por Bensasson, René V., Zoete, Vincent, Berthier, Gaston, Talalay, Paul, Dinkova-Kostova, Albena T.
Publicado em 2010

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

Por Calabrese, Vittorio, Cornelius, Carolin, Dinkova-Kostova, Albena T., Calabrese, Edward J., Mattson, Mark P.
Publicado em 2010

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells

Por Roubalová, Lenka, Dinkova-Kostova, Albena T., Biedermann, David, Křen, Vladimír, Ulrichová, Jitka, Vrba, Jiří
Publicado no Fitoterapia (2017)

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

Por Dinkova-Kostova, Albena T., Massiah, Michael A., Bozak, Richard E., Hicks, Ronald J., Talalay, Paul
Publicado em 2001

Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex

Por Kerns, Michelle L., DePianto, Daryle, Dinkova-Kostova, Albena T., Talalay, Paul, Coulombe, Pierre A.
Publicado em 2007

RAPID BODY WEIGHT GAIN INCREASES THE RISK OF ULTRAVIOLET RADIATION-INDUCED SKIN CARCINOGENESIS IN SKH-1 HAIRLESS MICE

Por Dinkova-Kostova, Albena T., Fahey, Jed W., Jenkins, Stephanie N., Wehage, Scott L., Talalay, Paul
Publicado em 2008

Oral Azathioprine Leads to Higher Incorporation of 6-Thioguanine in DNA of Skin than Liver: The Protective Role of the Keap1/Nrf2/ARE Pathway

Por Kalra, Sukirti, Zhang, Ying, Knatko, Elena V., Finlayson, Stewart, Yamamoto, Masayuki, Dinkova-Kostova, Albena T.
Publicado em 2011

The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics

Por Dinkova-Kostova, Albena T., Baird, Liam, Holmström, Kira M., Meyer, Colin J., Abramov, Andrey Y.
Publicado no Biochem Soc Trans (2015)

NRF2 as an Emerging Therapeutic Target

Por Copple, Ian M., Dinkova-Kostova, Albena T., Kensler, Thomas W., Liby, Karen T., Wigley, W. Christian
Publicado no Oxid Med Cell Longev (2017)