Simple and Rapid HPLC Separation and Quantification of Flavonoid, Flavonolignans, and 2,3-Dehydroflavonolignans in Silymarin

Por Petrásková, Lucie, Káňová, Kristýna, Biedermann, David, Křen, Vladimír, Valentová, Kateřina
Publicado no Foods (2020)

Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins

Por Huang, Guozheng, Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír, Decker, Michael
Publicado no Beilstein J Org Chem (2016)

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells

Por Roubalová, Lenka, Dinkova-Kostova, Albena T., Biedermann, David, Křen, Vladimír, Ulrichová, Jitka, Vrba, Jiří
Publicado no Fitoterapia (2017)

Differential Effects of the Flavonolignans Silybin, Silychristin and 2,3-Dehydrosilybin on Mesocestoides vogae Larvae (Cestoda) under Hypoxic and Aerobic In Vitro Conditions

Por Hrčková, Gabriela, Kubašková, Terézia Mačák, Benada, Oldřich, Kofroňová, Olga, Tumová, Lenka, Biedermann, David
Publicado no Molecules (2018)

Skin Protective Activity of Silymarin and its Flavonolignans

Por Vostálová, Jitka, Tinková, Eva, Biedermann, David, Kosina, Pavel, Ulrichová, Jitka, Rajnochová Svobodová, Alena
Publicado no Molecules (2019)

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

Por Agarwal, Chapla, Wadhwa, Ritambhara, Deep, Gagan, Biedermann, David, Gažák, Radek, Křen, Vladimír, Agarwal, Rajesh
Publicado em 2013

Flavonolignans As a Novel Class of Sodium Pump Inhibitors

Por Kubala, Martin, Čechová, Petra, Geletičová, Jaroslava, Biler, Michal, Štenclová, Tereza, Trouillas, Patrick, Biedermann, David
Publicado no Front Physiol (2016)

Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties

Por Chambers, Christopher S., Biedermann, David, Valentová, Kateřina, Petrásková, Lucie, Viktorová, Jitka, Kuzma, Marek, Křen, Vladimír
Publicado no Antioxidants (Basel) (2019)

Dermal Delivery of Selected Polyphenols from Silybum marianum. Theoretical and Experimental Study

Por Kosina, Pavel, Paloncýová, Markéta, Rajnochová Svobodová, Alena, Zálešák, Bohumil, Biedermann, David, Ulrichová, Jitka, Vostálová, Jitka
Publicado no Molecules (2018)

Modulation of Skin Inflammatory Response by Active Components of Silymarin

Por Juráňová, Jana, Aury-Landas, Juliette, Boumediene, Karim, Baugé, Catherine, Biedermann, David, Ulrichová, Jitka, Franková, Jana
Publicado no Molecules (2018)

Regioselective Alcoholysis of Silychristin Acetates Catalyzed by Lipases ‡

Por Vavříková, Eva, Gavezzotti, Paolo, Purchartová, Kateřina, Fuksová, Kateřina, Biedermann, David, Kuzma, Marek, Riva, Sergio, Křen, Vladimír
Publicado no Int J Mol Sci (2015)

In-Vitro Activity of Silybin and Related Flavonolignans against Leishmania infantum and L. donovani

Por Olías-Molero, Ana Isabel, Jiménez-Antón, María Dolores, Biedermann, David, Corral, María J., Alunda, José María
Publicado no Molecules (2018)

Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice

Por Šuk, Jakub, Jašprová, Jana, Biedermann, David, Petrásková, Lucie, Valentová, Kateřina, Křen, Vladimír, Muchová, Lucie, Vítek, Libor
Publicado no Oxid Med Cell Longev (2019)

Silibinin and its 2,3-Dehydro-derivative Inhibit Basal Cell Carcinoma Growth via Suppression of Mitogenic Signaling and Transcription Factors Activation

Por Tilley, Cynthia, Deep, Gagan, Agarwal, Chapla, Wempe, Michael F, Biedermann, David, Valentová, Kateřina, Kren, Vladimir, Agarwal, Rajesh
Publicado no Mol Carcinog (2014)

Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

Por Roubalová, Lenka, Biedermann, David, Papoušková, Barbora, Vacek, Jan, Kuzma, Marek, Křen, Vladimír, Ulrichová, Jitka, Dinkova-Kostova, Albena T., Vrba, Jiří
Publicado no Chem Biol Interact (2016)

Molecular Defects in Cardiac Myofilament Ca(2+)-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin

Por Sheehan, Alice, Messer, Andrew E., Papadaki, Maria, Choudhry, Afnan, Kren, Vladimír, Biedermann, David, Blagg, Brian, Khandelwal, Anuj, Marston, Steven B.
Publicado no Front Physiol (2018)

cis–trans Isomerization of silybins A and B

Por Novotná, Michaela, Gažák, Radek, Biedermann, David, Di Meo, Florent, Marhol, Petr, Kuzma, Marek, Bednárová, Lucie, Fuksová, Kateřina, Trouillas, Patrick, Křen, Vladimír
Publicado em 2014

Antioxidant, Anti-Inflammatory, and Multidrug Resistance Modulation Activity of Silychristin Derivatives

Por Viktorová, Jitka, Dobiasová, Simona, Řehořová, Kateřina, Biedermann, David, Káňová, Kristýna, Šeborová, Karolína, Václavíková, Radka, Valentová, Kateřina, Ruml, Tomáš, Křen, Vladimír, Macek, Tomáš
Publicado no Antioxidants (Basel) (2019)

Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential

Por Dobiasová, Simona, Řehořová, Kateřina, Kučerová, Denisa, Biedermann, David, Káňová, Kristýna, Petrásková, Lucie, Koucká, Kamila, Václavíková, Radka, Valentová, Kateřina, Ruml, Tomáš, Macek, Tomáš, Křen, Vladimír, Viktorová, Jitka
Publicado no Antioxidants (Basel) (2020)

The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo

Por Pourová, Jana, Applová, Lenka, Macáková, Kateřina, Vopršalová, Marie, Migkos, Thomas, Bentanachs, Roger, Biedermann, David, Petrásková, Lucie, Tvrdý, Václav, Hrubša, Marcel, Karlíčková, Jana, Křen, Vladimír, Valentová, Kateřina, Mladěnka, Přemysl
Publicado no Nutrients (2019)