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Flavonolignans As a Novel Class of Sodium Pump Inhibitors
We examined the inhibitory effects of three flavonolignans and their dehydro- derivatives, taxifolin and quercetin on the activity of the Na(+)/K(+)-ATPase (NKA). The flavonolignans silychristin, dehydrosilychristin and dehydrosilydianin inhibited NKA with IC(50) of 110 ± 40 μM, 38 ± 8 μM, and 36 ±...
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| Publicat a: | Front Physiol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4812144/ https://ncbi.nlm.nih.gov/pubmed/27065883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00115 |
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