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Efficacy ranking of triterpenoids as inducers of a cytoprotective enzyme and as inhibitors of a cellular inflammatory response via their electron affinity and their electrophilicity index

Electron affinity (EA) and electrophilicity index (ω) of 16 synthetic triterpenoids (TP), previously identified as inducers of cytoprotective enzymes and as inhibitors of cellular inflammatory responses, have been calculated by the molecular orbital method. Linear correlations were obtained by plott...

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Detalhes bibliográficos
Main Authors: Bensasson, René V., Zoete, Vincent, Berthier, Gaston, Talalay, Paul, Dinkova-Kostova, Albena T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199116/
https://ncbi.nlm.nih.gov/pubmed/20433811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.04.026
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