Electrophilic tuning of the chemoprotective natural product sulforaphane

Sulforaphane [1-isothiocyanato-4-(methylsulfinyl)butane], a naturally occurring isothiocyanate derived from cruciferous vegetables, is a highly potent inducer of phase 2 cytoprotective enzymes and can protect against electrophiles including carcinogens, oxidative stress, and inflammation. The mechan...

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Hauptverfasser: Ahn, Young-Hoon, Hwang, Yousang, Liu, Hua, Wang, Xiu Jun, Zhang, Ying, Stephenson, Katherine K., Boronina, Tatiana N., Cole, Robert N., Dinkova-Kostova, Albena T., Talalay, Paul, Cole, Philip A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906893/
https://ncbi.nlm.nih.gov/pubmed/20439747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004104107
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