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The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner

BACKGROUND: The isothiocyanate sulforaphane (SFN) has multiple protein targets in mammalian cells, affecting processes of fundamental importance for the maintenance of cellular homeostasis, among which are those regulated by the stress response transcription factor nuclear factor erythroid 2 p45-rel...

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Dettagli Bibliografici
Pubblicato in:Phytomedicine
Autori principali: Zhang, Ying, Gilmour, Amy, Ahn, Young-Hoon, de la Vega, Laureano, Dinkova-Kostova, Albena T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Urban & Fischer Verlag 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106549/
https://ncbi.nlm.nih.gov/pubmed/31409554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phymed.2019.153062
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