The role of crystallography in drug design

Por Deschamps, Jeffrey R.
Publicado em 2005

X-Ray Crystallography of Chemical Compounds

Por Deschamps, Jeffrey R.
Publicado em 2009

Synthesis of Conformationally Locked L-Deoxythreosyl Phosphonate Nucleosides Built on a Bicyclo[3.1.0]hexane Template

Por Saneyoshi, Hisao, Deschamps, Jeffrey R., Marquez, Victor E.
Publicado em 2010

1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogs. A promising class of monoamine uptake inhibitors

Por Meltzer, Peter C., Butler, David, Deschamps, Jeffrey R., Madras, Bertha K.
Publicado em 2006

Synthesis of 1,2-dihydro-2-oxo-4-quinolinyl phosphates from 2-acyl-benzoic acids

Por He, Xinhua, Aglio, Tharcilla, Deschamps, Jeffrey R., Rai, Rachita, Xue, Fengtian
Publicado no Tetrahedron Lett (2015)

Crystal structure of catena-poly[[chlorido­(4,4′-dimethyl-2,2′-bi­pyridine-κ(2) N,N′)copper(II)]-μ-chlorido]

Por Nita, Rafaela, Deschamps, Jeffrey R., Trammell, Scott A., Knight, D. Andrew
Publicado no Acta Crystallogr E Crystallogr Commun (2015)

Chiral resolution and absolute configuration of the enantiomers of the psychoactive “designer drug” 3,4-methylenedioxypyrovalerone

Por Suzuki, Masaki, Deschamps, Jeffrey R., Jacobson, Arthur E., Rice, Kenner C.
Publicado no Chirality (2015)

PROBES FOR NARCOTIC RECEPTOR MEDIATED PHENOMENA. 38.(1) AN EXPEDITIOUS SYNTHESIS OF RAC-CIS-4a-ETHYL-2-METHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL AND RAC-CIS-2-METH...

Por Iyer, Malliga R., Deschamps, Jeffrey R., Jacobson, Arthur E., Rice, Kenner C.
Publicado em 2009

Diastereoselective One-Pot Synthesis of 7- and 8-Substituted 5-Phenylmorphans

Por Lim, Hwan Jung, Deschamps, Jeffrey R., Jacobson, Arthur E., Rice, Kenner C.
Publicado em 2011

Expeditious Synthesis, Enantiomeric Resolution and Enantiomer Functional Characterization of (4-(4-bromophenyl)-3a, 4, 5, 9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP...

Por Thakur, Ganesh A., Kulkarni, Abhijit R., Deschamps, Jeffrey R., Papke, Roger L.
Publicado em 2013

Nature-Inspired Stereospecific Total Synthesis of P-(+)-Dispegatrine as well as the Total Synthesis of Four Other Monomeric Sarpagine Indole Alkaloids

Por Edwankar, Chitra R., Edwankar, Rahul V., Deschamps, Jeffrey R., Cook, James M.
Publicado em 2012

Synthesis of Enantiopure 10-Nornaltrexones in the Search for Toll-like Receptor 4 Antagonists and Opioid Ligands

Por Selfridge, Brandon R., Deschamps, Jeffrey R., Jacobson, Arthur E., Rice, Kenner C.
Publicado em 2014

General Strategy for Synthesis of C-19 Methyl-Substituted Sarpagine/Macroline/Ajmaline Indole Alkaloids Including Total Synthesis of 19(S),20(R)-Dihydroperaksine, 19(S),20(R)-Dihyd...

Por Edwankar, Rahul V., Edwankar, Chitra R., Deschamps, Jeffrey R., Cook, James M.
Publicado no J Org Chem (2014)

Application of silver N-heterocyclic carbene complexes in O-glycosidation reactions

Por Talisman, Ian J., Kumar, Vineet, Deschamps, Jeffrey R., Frisch, Mark, Malhotra, Sanjay V.
Publicado em 2011

CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist

Por Chen, Jianyong, Collins, Gregory T., Levant, Beth, Woods, James, Deschamps, Jeffrey R., Wang, Shaomeng
Publicado em 2011

Synthesis of 8-thiabicyclo[3.2.1]octanes and Their Binding Affinity for the Dopamine and Serotonin Transporters

Por Pham-Huu, Duy-Phong, Deschamps, Jeffrey R., Liu, Shanghao, Madras, Bertha K., Meltzer, Peter C.
Publicado em 2006

Functionalization of the 6,14-bridge of the orvinols. 3.(1) Preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols

Por Wu, Huifang, Smith, Trudy A., Huang, Hongyan, Wang, Jia Bei, Deschamps, Jeffrey R., Coop, Andrew
Publicado em 2007

Brønsted Acid Mediated Cyclization of Enaminones. Rapid and Efficient Access to the Tetracyclic Framework of the Strychnos Alkaloids

Por Edwankar, Rahul V., Edwankar, Chitra R., Namjoshi, Ojas A., Deschamps, Jeffrey R., Cook, James M.
Publicado em 2012

Detection of Explosives in a Dynamic Marine Environment Using a Moored TNT Immunosensor

Por Charles, Paul T., Adams, André A., Deschamps, Jeffrey R., Veitch, Scott, Hanson, Al, Kusterbeck, Anne W.
Publicado em 2014

Synthesis of Aza and Carbocyclic β-Carbolines for the Treatment of Alcohol Abuse. Regiospecific Solution to The Problem of 3,6-Disubstituted β-and Aza-β-carboline Specificity

Por Phani Babu Tiruveedhula, V. V. N., Methuku, Kashi Reddy, Deschamps, Jeffrey R., Cook, James M.
Publicado no Org Biomol Chem (2015)