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Diastereoselective One-Pot Synthesis of 7- and 8-Substituted 5-Phenylmorphans
[Image: see text] Novel 7- and 8-alkyl and aryl substituted 5-phenylmorphans were synthesized from substituted allyl halides and N-benzyl-4-aryl-1,2,3,6-tetrahydropyridine by a highly efficient and diastereoselective reaction series, “one-pot” alkylation and ene-imine cyclization followed by sodium...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351792/ https://ncbi.nlm.nih.gov/pubmed/21905747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2021862 |
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