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Probes for Narcotic Receptor Mediated Phenomena. 39.1 Enantiomeric N-Substituted Benzofuro[2,3-c]pyridin-6-ols: Synthesis and Topological Relationship to Oxide-bridged Phenylmorphans2
Enantiomers of N-substituted benzofuro[2,3-c]pyridin-6-ols have been synthesized and the subnanomolar affinity and potent agonist activity of the known racemic N-phenethyl substituted benzofuro[2,3-c]pyridin-6-ol can now be ascribed to the 4aS,9aR enantiomer. The energy minimized structures suggest...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788676/ https://ncbi.nlm.nih.gov/pubmed/19627147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9004225 |
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