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Probes for narcotic receptor mediated phenomena. 48. C7- and C8-Substituted 5-phenylmorphan opioids from diastereoselective alkylation
The exploration of the effect of substituents at C7 and C8 of the 5-phenylmorphans on their affinity for opioid receptors was enabled by our recently introduced “one pot” diastereoselective synthesis that provided C7-oxo, hydroxy and alkyl substituents, C8-alkyl substituted 5-phenylmorphans, and com...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817624/ https://ncbi.nlm.nih.gov/pubmed/23880358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.06.030 |
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