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Probes for narcotic receptor mediated phenomena 49. N-Substituted rac-cis-4a-arylalkyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols

Racemic N-substituted -1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols containing cis-4aaralkyl groups were explored as probes for opioid receptors. Specifically cis-4a-phenylpropyl, -phenylbutyl, and- phenylpentyl groups coupled with widely varied substituents on the nitrogen atom were synthes...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Iyer, Malliga R., Rothman, Richard B., Dersch, Christina M., Jacobson, Arthur E., Rice, Kenner C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348089/
https://ncbi.nlm.nih.gov/pubmed/25599950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.01.025
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