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Probes for narcotic receptor mediated phenomena. 47.(1) Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c] pyridin-6-ols

A series of N-methyl rac-cis-4a-aralkyl- and alkyl-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols have been prepared (2a–l) using a simple previously designed synthetic route, in order to find a ligand that would interact with both μ- and δ-opioid receptors. A C4a-phenethyl derivat...

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Detalhes bibliográficos
Principais autores: Iyer, Malliga R., Rothman, Richard B., Dersch, Christina M., Jacobson, Arthur E., Rice, Kenner C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769098/
https://ncbi.nlm.nih.gov/pubmed/23618710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.02.060
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