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The role of crystallography in drug design
Structure and function are intimately related. Nowhere is this more important than the area of bioactive molecules. It has been shown that the enantioselectivity of an enzyme is directly related to its chirality. X-ray crystallography is the only method for determining the “absolute” configuration o...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2005
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750950/ https://ncbi.nlm.nih.gov/pubmed/16594633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070478 |
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