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The role of crystallography in drug design

Structure and function are intimately related. Nowhere is this more important than the area of bioactive molecules. It has been shown that the enantioselectivity of an enzyme is directly related to its chirality. X-ray crystallography is the only method for determining the “absolute” configuration o...

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Detalhes bibliográficos
Autor principal: Deschamps, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750950/
https://ncbi.nlm.nih.gov/pubmed/16594633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj070478
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