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General Strategy for Synthesis of C-19 Methyl-Substituted Sarpagine/Macroline/Ajmaline Indole Alkaloids Including Total Synthesis of 19(S),20(R)-Dihydroperaksine, 19(S),20(R)-Dihydroperaksine-17-al, and Peraksine

[Image: see text] A detailed account of the development of a general strategy for synthesis of the C-19 methyl-substituted alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine-17-al (1), 19(S),20(R)-dihydroperaksine (2), and peraksine (6) is presented. Efforts directed toward the tota...

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Bibliographic Details
Published in:J Org Chem
Main Authors: Edwankar, Rahul V., Edwankar, Chitra R., Deschamps, Jeffrey R., Cook, James M.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227583/
https://ncbi.nlm.nih.gov/pubmed/25247616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo5016163
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