Regiospecific, Enantiospecific Total Synthesis of C-19 Methyl Substituted Sarpagine Alkaloids Dihydroperaksine-17-al and Dihydroperaksine

Por Edwankar, Rahul V., Edwankar, Chitra R., Deschamps, Jeffrey, Cook, James M.
Publicado em 2011

Nature-Inspired Stereospecific Total Synthesis of P-(+)-Dispegatrine as well as the Total Synthesis of Four Other Monomeric Sarpagine Indole Alkaloids

Por Edwankar, Chitra R., Edwankar, Rahul V., Deschamps, Jeffrey R., Cook, James M.
Publicado em 2012

General Strategy for Synthesis of C-19 Methyl-Substituted Sarpagine/Macroline/Ajmaline Indole Alkaloids Including Total Synthesis of 19(S),20(R)-Dihydroperaksine, 19(S),20(R)-Dihyd...

Por Edwankar, Rahul V., Edwankar, Chitra R., Deschamps, Jeffrey R., Cook, James M.
Publicado no J Org Chem (2014)

Stereospecific Approach to the Synthesis of Ring-A Oxygenated Sarpagine Indole Alkaloids. Total Synthesis of the Dimeric Indole Alkaloid P-(+)-Dispegatrine and Six Other Monomeric...

Por Edwankar, Chitra R., Edwankar, Rahul V., Namjoshi, Ojas A., Liao, Xuebin, Cook, James M.
Publicado em 2013

Brønsted Acid Mediated Cyclization of Enaminones. Rapid and Efficient Access to the Tetracyclic Framework of the Strychnos Alkaloids

Por Edwankar, Rahul V., Edwankar, Chitra R., Namjoshi, Ojas A., Deschamps, Jeffrey R., Cook, James M.
Publicado em 2012

NOVEL POSITIVE ALLOSTERIC MODULATORS OF GABAA RECEPTORS: DO SUBTLE DIFFERENCES IN ACTIVITY AT α1 PLUS α5 VERSUS α2 PLUS α3 SUBUNITS ACCOUNT FOR DISSIMILARITIES IN BEHAVIORAL EFFECT...

Por Savić, Miroslav M., Majumder, Samarpan, Huang, Shengming, Edwankar, Rahul V., Furtmüller, Roman, Joksimović, Srđan, Clayton, Terry, Ramerstorfer, Joachim, Milinković, Marija M., Roth, Bryan L., Sieghart, Werner, Cook, James M.
Publicado em 2010

Antiseizure Activity of Novel Gamma-Aminobutyric Acid (A) Receptor Subtype-Selective Benzodiazepine Analogs in Mice and Rat Models

Por Rivas, Felix M., Stables, James P., Murphree, Lauren, Edwankar, Rahul V., Edwankar, Chitra R., Huang, Shengming, Jain, Hiteshkumar D., Zhou, Hao, Majumder, Samarpan, Sankar, Subramanian, Roth, Bryan L., Ramerstorfer, Joachim, Furtmuller, Roman, Sieghart, Werner, Cook, James M.
Publicado em 2009

Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure

Por Fischer, Bradford D., Licata, Stephanie C., Edwankar, Rahul V., Wang, Zhi-Jian, Huang, Shengming, He, Xiaohui, Yu, Jianming, Zhou, Hao, Johnson, Edward M., Cook, James M., Furtmüller, Roman, Ramerstorfer, Joachim, Sieghart, Werner, Roth, Bryan L., Majumder, Samarpan, Rowlett, James K.
Publicado em 2010