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Synthesis of 8-thiabicyclo[3.2.1]octanes and Their Binding Affinity for the Dopamine and Serotonin Transporters

Cocaine is a potent stimulant of the central nervous system. Its reinforcing and stimulant properties have been associated with inhibition of the dopamine transporter (DAT) on presynaptic neurons. In the search for medications for cocaine abuse, we have prepared 2-carbomethoxy-3-aryl-8-thiabicyclo[3...

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Bibliografski detalji
Glavni autori: Pham-Huu, Duy-Phong, Deschamps, Jeffrey R., Liu, Shanghao, Madras, Bertha K., Meltzer, Peter C.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829488/
https://ncbi.nlm.nih.gov/pubmed/17070057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.10.016
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