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Development of 3-Phenyltropane Analogs with High Affinity for the Dopamine and Serotonin Transporters and Low Affinity for the Norepinephrine Transporter

Previous studies showed that the mixed monoamine transporter inhibitor (6, RTI-112) reduced cocaine self-administration at a high level of serotonin transporter (5-HTT) occupancy with no detectable dopamine transporter (DAT) occupancy. In this study, a series of 3β-(substituted phenyl)tropane-2β-car...

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Autors principals: Jin, Chunyang, Navarro, Hernán A., Carroll, F. Ivy
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841478/
https://ncbi.nlm.nih.gov/pubmed/19053748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801162z
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