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Animal models of depression in dopamine, serotonin and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions

Antidepressant drugs produce therapeutic actions and many of their side effects via blockade of the plasma membrane transporters for serotonin (SERT/SLC6A2), norepinephrine (NET/SLC6A1) and dopamine (DAT/SLC6A3). Many antidepressants block several ofthese transporters; some are more selective. Mouse...

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Main Authors: Perona, Maria T.G., Waters, Shonna, Hall, F. Scott, Sora, Ichiro, Lesch, Klaus-Peter, Murphy, Dennis L., Caron, Marc, Uhl, George R.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644662/
https://ncbi.nlm.nih.gov/pubmed/18690111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32830cd80f
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