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Serotonin/Dopamine Interactions in a Hyperactive Mouse: Reduced Serotonin Receptor 1B Activity Reverses Effects of Dopamine Transporter Knockout

Knockout (KO) mice that lack the dopamine transporter (SL6A3; DAT) display increased locomotion that can be attenuated, under some circumstances, by administration of drugs that normally produce psychostimulant-like effects, such as amphetamine and methylphenidate. These results have led to suggesti...

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Publicat a:PLoS One
Autors principals: Hall, Frank Scott, Sora, Ichiro, Hen, René, Uhl, George R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267809/
https://ncbi.nlm.nih.gov/pubmed/25514162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115009
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