Enterocyte progenitors can dedifferentiate to replace lost Lgr5(+) intestinal stem cells revealing that many different progenitor populations can regain stemness

Por Jones, Jennifer C., Dempsey, Peter J.
Publicado no Stem Cell Investig (2016)

Sequential and γ-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth

Por Stoeck, Alexander, Shang, Li, Dempsey, Peter J.
Publicado em 2010

ADAM Proteases and Gastrointestinal Function

Por Jones, Jennifer C., Rustagi, Shelly, Dempsey, Peter J.
Publicado no Annu Rev Physiol (2015)

Apical Enrichment of Human EGF Precursor in Madin-Darby Canine Kidney Cells Involves Preferential Basolateral Ectodomain Cleavage Sensitive to a Metalloprotease Inhibitor

Por Dempsey, Peter J., Meise, Katherine S., Yoshitake, Yoshino, Nishikawa, Katsuzo, Coffey, Robert J.
Publicado em 1997

TPN-associated intestinal epithelial cell atrophy is modulated by TLR4/EGF signaling pathways

Por Freeman, Jennifer J., Feng, Yongjia, Demehri, Farokh R., Dempsey, Peter J., Teitelbaum, Daniel H.
Publicado no FASEB J (2015)

Generation of Novel, Secreted Epidermal Growth Factor Receptor (EGFR/ErbB1) Isoforms Via Metalloprotease-Dependent Ectodomain Shedding and Exosome Secretion

Por Sanderson, Michael P., Keller, Sascha, Alonso, Angel, Riedle, Svenja, Dempsey, Peter J., Altevogt, Peter
Publicado no J Cell Biochem (2008)

TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival

Por Hilliard, Valda C., Frey, Mark R., Dempsey, Peter J., Peek, Richard M., Polk, D. Brent
Publicado em 2011

Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor

Por Dong, Jianying, Opresko, Lee K., Dempsey, Peter J., Lauffenburger, Douglas A., Coffey, Robert J., Wiley, H. Steven
Publicado em 1999

Distinct Mechanisms of Receptor and Nonreceptor Tyrosine Kinase Activation by Reactive Oxygen Species in Vascular Smooth Muscle Cells: Role of Metalloprotease and Protein Kinase C-...

Por Frank, Gerald D., Mifune, Mizuo, Inagami, Tadashi, Ohba, Motoi, Sasaki, Terukatsu, Higashiyama, Shigeki, Dempsey, Peter J., Eguchi, Satoru
Publicado em 2003

Receiver operating characteristic analysis for the detection of simulated microcalcifications on mammograms using hardcopy images

Por Lai, Chao-Jen, Shaw, Chris C, Whitman, Gary J, Yang, Wei T, Dempsey, Peter J, Nguyen, Victoria, Ice, Mary F
Publicado em 2006

N-Cadherin Promotes Recruitment and Migration of Neural Progenitor Cells from the SVZ Neural Stem Cell Niche into Demyelinated Lesions

Por Klingener, Michael, Chavali, Manideep, Singh, Jagdeep, McMillan, Nadia, Coomes, Alexandra, Dempsey, Peter J., Chen, Emily I., Aguirre, Adan
Publicado em 2014

Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines

Por Colombo, Alessio, Wang, Huanhuan, Kuhn, Peer-Hendrik, Page, Richard, Kremmer, Elisabeth, Dempsey, Peter J., Crawford, Howard C., Lichtenthaler, Stefan F.
Publicado no Neurobiol Dis (2012)

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

Por Zhang, Rong, Averboukh, Lidia, Zhu, Weimin, Zhang, Hong, Jo, Hakryul, Dempsey, Peter J., Coffey, Robert J., Pardee, Arthur B., Liang, Peng
Publicado em 1998

Deficiency of TNFα Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice

Por Gelling, Richard W., Yan, Wenbo, Al-Noori, Salwa, Pardini, Aaron, Morton, Gregory J., Ogimoto, Kayoko, Schwartz, Michael W., Dempsey, Peter J.
Publicado em 2008

Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition

Por Feng, Yongjia, Tsai, Yu-Hwai, Xiao, Weidong, Ralls, Matthew W., Stoeck, Alex, Wilson, Carole L., Raines, Elaine W., Teitelbaum, Daniel H., Dempsey, Peter J.
Publicado no Mol Cell Biol (2015)

A Lactobacillus rhamnosus GG-derived Soluble Protein, p40, Stimulates Ligand Release from Intestinal Epithelial Cells to Transactivate Epidermal Growth Factor Receptor

Por Yan, Fang, Liu, Liping, Dempsey, Peter J., Tsai, Yu-Hwai, Raines, Elaine W., Wilson, Carole L., Cao, Hailong, Cao, Zheng, Liu, LinShu, Polk, D. Brent
Publicado em 2013

Novel Role of Protein Kinase C Delta Tyr(311) Phosphorylation in Vascular Smooth Muscle Cell Hypertrophy by Angiotensin II

Por Nakashima, Hidekatsu, Frank, Gerald D., Shirai, Heigoro, Hinoki, Akinari, Higuchi, Sadaharu, Ohtsu, Haruhiko, Eguchi, Kunie, Sanjay, Archana, Reyland, Mary E., Dempsey, Peter J., Inagami, Tadashi, Eguchi, Satoru
Publicado em 2008

Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis

Por Yan, Fang, Cao, Hanwei, Chaturvedi, Rupesh, Krishna, Uma, Hobbs, Stuart S., Dempsey, Peter J., Peek, Richard M., Cover, Timothy L., Washington, M. Kay, Wilson, Keith T., Polk, D. Brent
Publicado em 2009

Comparison of Full-Field Digital Mammography and Screen-Film Mammography for Detection and Characterization of Simulated Small Masses

Por Yang, Wei T., Lai, Chao-Jen, Whitman, Gary J., Murphy, William A., Dryden, Mark J., Kushwaha, Anne C., Sahin, Aysegul A., Johnston, Dennis, Dempsey, Peter J., Shaw, Chris C.
Publicado em 2006

ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation

Por Schumacher, Michael A, Hedl, Matija, Abraham, Clara, Bernard, Jessica K, Lozano, Patricia R, Hsieh, Jonathan J, Almohazey, Dana, Bucar, Edie B, Punit, Shivesh, Dempsey, Peter J, Frey, Mark R
Publicado no Cell Death Dis (2017)