Generation of Novel, Secreted Epidermal Growth Factor Receptor (EGFR/ErbB1) Isoforms Via Metalloprotease-Dependent Ectodomain Shedding and Exosome Secretion

Exosomes are small membrane vesicles derived from intracellular multivescicular bodies (MVBs) that can undergo constitutive and regulated secretion from cells. Exosomes can also secrete soluble proteins through metalloprotease-dependent ectodomain shedding. In this study, we sought to determine whet...

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Bibliografiska uppgifter
I publikationen:J Cell Biochem
Huvudupphovsmän: Sanderson, Michael P., Keller, Sascha, Alonso, Angel, Riedle, Svenja, Dempsey, Peter J., Altevogt, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922250/
https://ncbi.nlm.nih.gov/pubmed/17910038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21569
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