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A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44
Ectodomain shedding is a proteolytic mechanism by which transmembrane molecules are converted into a soluble form. Cleavage is mediated by metalloproteases and proceeds in a constitutive or inducible fashion. Although believed to be a cell-surface event, there is increasing evidence that cleavage ca...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360713/ https://ncbi.nlm.nih.gov/pubmed/16229685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051013 |
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