A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

Ectodomain shedding is a proteolytic mechanism by which transmembrane molecules are converted into a soluble form. Cleavage is mediated by metalloproteases and proceeds in a constitutive or inducible fashion. Although believed to be a cell-surface event, there is increasing evidence that cleavage ca...

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Bibliographic Details
Main Authors: Stoeck, Alexander, Keller, Sascha, Riedle, Svenja, Sanderson, Michael P., Runz, Steffen, Le Naour, Francois, Gutwein, Paul, Ludwig, Andreas, Rubinstein, Eric, Altevogt, Peter
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360713/
https://ncbi.nlm.nih.gov/pubmed/16229685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051013
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