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Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

The L1 adhesion molecule plays an important role in axon guidance and cell migration in the nervous system. L1 is also expressed by many human carcinomas. In addition to cell surface expression, the L1 ectodomain can be released by a metalloproteinase, but the biological function of this process is...

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Detalhes bibliográficos
Main Authors: Mechtersheimer, Sabine, Gutwein, Paul, Agmon-Levin, Nancy, Stoeck, Alexander, Oleszewski, Matthias, Riedle, Svenja, Postina, Rolf, Fahrenholz, Falk, Fogel, Mina, Lemmon, Vance, Altevogt, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198870/
https://ncbi.nlm.nih.gov/pubmed/11706054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200101099
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